Holly Macintosh is sitting round her kitchen table with her oldest friends - friends she hasn't seen since school - now reunited by an unexpected tragedy and catching up on the past 20 years.
On the surface, they are all successful and happy. But scratch a little deeper after that extra glass of wine and it's not quite so straightforward: Paul and Anna are struggling to have a baby, Saffron the actress is still waiting for that really big break that - at 39 - is looking less and less likely, and Olivia, always the wallflower of the group, is newly single and mourning her lost love.
And what about Holly Mac? Can she and her husband Marcus get their marriage back on track for the sake of the children? Or has someone just come back into her life who will change everything forever?