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  • Published: 15 February 2006
  • ISBN: 9780375727047
  • Imprint: Knopf US
  • Format: Paperback
  • Pages: 272
  • RRP: $32.99

Change of Heart

Unraveling the Mysteries of Cardiovascular Disease



The fascinating story of a revolution in medicine--how Americans and the world learned to understand and fight heart disease. FIRST TIME IN PAPERBACK.

A Change of Heart is a detailed account of the revolutionary Framingham Heart study — which, over the years, has provided conclusive evidence that cardiovascular disease is largely the result of measurable and modifiable risk factors. First begun in 1948, not long after Franklin Delano Roosevelt succumbed to a massive stroke, the study of over 5,000 citizens of Framingham, Massachusetts, changed the course of medical history. The lessons learned in Framingham allow each of us to control our risk of heart disease and stroke, two of the leading causes of death in the United States. Here is a clear-eyed and intriguing assessment of the achievements of this study and of its continuing importance to our health today.

  • Published: 15 February 2006
  • ISBN: 9780375727047
  • Imprint: Knopf US
  • Format: Paperback
  • Pages: 272
  • RRP: $32.99

Praise for Change of Heart

"This account of the Framingham study...does justice to the courage and commitment of both the medical scientists and the patients who contributed so much to advancing the field of cardiology...The book is at its best in delineating the study's contrbution to preventative cardiology, particularly its discovery that there is a vast difference between an average and a desirable state of health." -The Boston Globe