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  • Published: 17 November 2020
  • ISBN: 9780262044615
  • Imprint: MIT Press Academic
  • Format: Hardback
  • Pages: 264
  • RRP: $110.00
Categories:

Changing Connectomes

Evolution, Development, and Dynamics in Network Neuroscience




An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages.

An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages.

The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development. 

Drawing on a range of results from experimental, clinical, and computational studies, Kaiser describes changes during healthy brain maturation and during brain network disorders (including such neurodevelopmental conditions as schizophrenia and depression), brain injury, and neurodegenerative disorders including dementia. He argues that brain stimulation is an area where understanding connectome development could help in assessing long-term effects of interventions. Changing Connectomes is a suitable starting point for researchers who are new to the field of connectomics, and also for researchers who are interested in the link between brain network organization and brain and cognitive development in health and disease. Matlab/Octave code examples available at the MIT Press website will allow computational neuroscience researchers to understand and extend the shown mechanisms of connectome development.

  • Published: 17 November 2020
  • ISBN: 9780262044615
  • Imprint: MIT Press Academic
  • Format: Hardback
  • Pages: 264
  • RRP: $110.00
Categories:

Praise for Changing Connectomes

"The work is original in its emphasis on underlying mechanisms and computational simulations, as well as in its coverage of connectivity development and lifespan changes in health and disease." --Arjen Van Ooyen (Vrije Univ. Amsterdam)

"I am extremely enthusiastic about this project. The author outlines an accessible range of information that will appeal broadly to biologists and theorists interested in brain network connectivity."--
Hillis Cline (Scripps Research Institute, La Jolla)

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